Ist "door to door" in diesem Zusammenhang richtig?

Yes.

But are you asking about the German or the English? You've put the English in as the source language, and German in the "Correct?" field.

Just wanted to note, in case you wanted to use a phrase like in the OP but without the parentheses: I don't think "It takes me X hours" is generally used with "to commute", at least not in AE. "It takes me..." (X amount of time) is fine, but without commute. Concerning the term "commute," I'm far more familiar (having grown up in the US) with "I commute [verb] X hours " and "I have an X-hour commute" [noun].

More detail: "Commute" as a noun is most likely to be found when the commute is mentioned as an attribute of, say, one's job, or one's daily routine, or similar: "I have to get up early because I have a two-and-a-half hour commute." "The people are great and the pay is pretty good, but I do have a ..."

If the daily journey itself is the main focus, use of the verb is more likely; e.g.: "I commute two and a half hours every dang day!"

(Caveat: This is off the top of my head, or from my gut feeling, not out of any rule book.)

Edit: Long story short, I wanted to say "It takes me two hours to get to work" sounds more idiomatic to me that "It takes me two hours to commute to work" - but I'm starting to wonder if other sees (or hear) that differently...

Von Tür zu Tür empfinde ich als vollkommen idiomatisch und beziehe es auf die jeweilige Eingangstür des Gebäudes.

Warum übrigens pendele? Ich pendle.

Duden meint: ich pend[e]le

Ich spreche es tatsächlich mit dem -e- aus (also mit einem Schwa), wohl weil d und l weit genug voneinander entfernt gebildet werden, dass das -e- die Aussprache erleichtert. (Hingegen sage ich "ich schnipple", "ich wackle").

#12: Ob [es] noch zusätzliche Betonung braucht, dass tatsächlich die gesamte Strecke inkl. Fußweg zum und vom Verkehrsmittel gemeint ist, müssen die NES entscheiden.

I wouldn't really expect it (and haven't so far heard it) except in cases where there's a sizable difference between, say, the drive -- or more commonly, the flight -- itself and the entire journey. A flight between one city and another takes X hours, but when you add the time getting to/from the airport and of course the need to check in an hour or two before take-off, the difference can be considerable.

As for driving to work, I've only heard the expression used by someone I know who lives in a suburb and signed up for a carpooling option rather than driving her own car to and from work every day. She had a 10-minute drive from home to the meeting place for the carpool, and then a 20-minute walk from the carpool drop-off point in "the big city" to her office. She told me her commute wasn't any faster door-to-door, but there were fewer cars on the road that way and she enjoyed the brief walks.

#12 and #17  Ob [es] noch zusätzliche Betonung braucht, dass tatsächlich die gesamte Strecke inkl. Fußweg zum und vom Verkehrsmittel gemeint ist, müssen die NES entscheiden.

Is this any different in German? I would always expect 'commute time' to automatically include the walk on either side.

'It takes me an hour to get to work' :

If you're driving or cycling, and then there's no walk on either side: it's 1hr door to door. On public transport, you're talking about total journey time including walk on either side, so it's also door to door.

If you want to refer to just the journey by public transport, then you'd say so clearly ('I have a 40 minute tube journey every morning - so I can get lots of reading done'; 'I'm only on the tube for 5 minutes, not long enough to bother sitting down').

So, no, you don't need to say 'door to door'. It's a common enough expression though!